Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396743 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3MAPT | |
| SCHEMBL12263289 | 0.83 | HPGD (0.46) | SMN1; SMN2ALDH1A1HPGDTSHRCA1 | |
| SCHEMBL12263449 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3MAPT | |
| SCHEMBL2396562 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3NPC1 | |
| SCHEMBL2396695 | 0.78 | SCN1A (0.49) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3PTPN1 | |
| SCHEMBL12263260 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3NPC1 | |
| SCHEMBL12987761 | 0.77 | HRH3 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9APTPN1 | |
| SCHEMBL12263343 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3MAPT | |
| SCHEMBL12263297 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3MAPT | |
| SCHEMBL12263340 | 0.77 | RXRA (0.48) | SMN1; SMN2ALDH1A1ALDH1A2ALDH1A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022208-B2 | Benzene derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022208-B2 | Benzene derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090054352-A1 | BENZENE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054352-A1 | BENZENE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054352-A1 | BENZENE DERIVATIVE OR SALT THEREOF | F12, F2, SERPINC1 | SMN1; SMN2 4094/4885ALDH1A1 3722/4885ALDH1A2 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.