Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.54 |
| ▸ | DUT | P33316 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919848 | 0.94 | KIF11 (0.55) | KIF11KCNN4DUTSIGMAR1 | |
| SCHEMBL9926038 | 0.91 | KIF11 (0.67) | KIF11KCNN4DUT | |
| SCHEMBL28742617 | 0.88 | KCNN4 (0.57) | KIF11KCNN4SIGMAR1 | |
| SCHEMBL12264131 | 0.84 | KIF11 (0.74) | KIF11KCNN4DUTMIF | |
| SCHEMBL9654002 | 0.81 | KIF11 (0.46) | KIF11KCNN4DUTSMN1; SMN2 | |
| SCHEMBL1809571 | 0.80 | KIF11 (0.63) | KIF11KCNN4DUTMIF | |
| SCHEMBL12264133 | 0.79 | KIF11 (0.68) | KIF11KCNN4DUTSIGMAR1 | |
| SCHEMBL29679194 | 0.77 | KIF11 (0.65) | KIF11KCNN4DUTSIGMAR1 | |
| SCHEMBL147990 | 0.77 | KIF11 (0.65) | KIF11KCNN4DUTSMN1; SMN2 | |
| SCHEMBL3111880 | 0.77 | KIF11 (0.59) | KIF11KCNN4DUTMIFSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |