Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.67 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.46 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264129 | 0.91 | KIF11 (0.61) | KIF11KCNN4DUT | |
| SCHEMBL22919848 | 0.85 | KIF11 (0.55) | KIF11KCNN4DUT | |
| SCHEMBL1105545 | 0.81 | KIF11 (1.00) | KIF11KCNN4DUTTAAR1 | |
| SCHEMBL28742617 | 0.80 | KCNN4 (0.57) | KIF11KCNN4 | |
| Bromide SCHEMBL5339582 | 0.79 | KIF11 (0.96) | KIF11KCNN4DUTTAAR1 | |
| SCHEMBL12264131 | 0.76 | KIF11 (0.74) | KIF11KCNN4DUTTAAR1 | |
| SCHEMBL2283152 | 0.76 | KIF11 (0.74) | KIF11KCNN4DUT | |
| SCHEMBL9617559 | 0.74 | KIF11 (0.78) | KIF11KCNN4DUTTAAR1 | |
| SCHEMBL15160759 | 0.74 | KIF11 (0.71) | KIF11KCNN4DUT | |
| SCHEMBL9654002 | 0.73 | KIF11 (0.46) | KIF11KCNN4DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149653-A1 | MULTIFUNCTIONAL LINKERS AND METHODS FOR THE USE THEREOF | RGO BIOSCIENCE LLC | 2012-06-14 | — | — | US | disclosed |
| US-20120149732-A1 | MULTIFUNCTIONAL LINKERS AND METHODS FOR THE USE THEREOF | RGO BIOSCIENCE LLC | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149732-A1 | MULTIFUNCTIONAL LINKERS AND METHODS FOR THE USE THEREOF | ILK, PAICS, THEM6 | KIF11 3247/4885KCNN4 4751/4885DUT 404/4885 |
| US-20120149653-A1 | MULTIFUNCTIONAL LINKERS AND METHODS FOR THE USE THEREOF | ILK, PAICS, THEM6 | KIF11 3247/4885KCNN4 4751/4885DUT 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.