Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264129 | 0.81 | KIF11 (0.61) | KIF11KCNN4SMN1; SMN2DUT | |
| SCHEMBL29679194 | 0.81 | KIF11 (0.65) | KIF11KCNN4MEN1KMT2ADUT | |
| SCHEMBL147990 | 0.77 | KIF11 (0.65) | KIF11KCNN4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22919848 | 0.76 | KIF11 (0.55) | KIF11KCNN4DUT | |
| SCHEMBL12264131 | 0.75 | KIF11 (0.74) | KIF11KCNN4MEN1KMT2ADUT | |
| SCHEMBL9008769 | 0.75 | KIF11 (0.36) | KIF11KCNN4MEN1KMT2AALDH1A1 | |
| SCHEMBL6251086 | 0.74 | KIF11 (0.57) | KIF11KCNN4DUT | |
| SCHEMBL6066207 | 0.74 | KIF11 (0.41) | KIF11KCNN4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9926038 | 0.73 | KIF11 (0.67) | KIF11KCNN4DUT | |
| SCHEMBL9617559 | 0.73 | KIF11 (0.78) | KIF11KCNN4MEN1KMT2ADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496641-A2 | Cobalt complexes as anticancer agents | WARNER-LAMBERT COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |