Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 11/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264731 | 0.89 | LMNA (0.41) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL27829237 | 0.87 | DRD2 (0.42) | FOLH1LMNATHRBCYP2C19TYMP | |
| SCHEMBL12264732 | 0.85 | LMNA (0.42) | DGAT1FOLH1LMNATHRBCYP2C19 | |
| SCHEMBL12264734 | 0.83 | CYP3A4 (0.35) | DGAT1FOLH1CYP3A4CYP2D6OPRK1 | |
| SCHEMBL12264733 | 0.82 | EGFR (0.36) | DGAT1FOLH1CYP3A4CYP2D6OPRK1 | |
| SCHEMBL941529 | 0.81 | LMNA (0.46) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL12427963 | 0.78 | TYMP (0.43) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL12427881 | 0.78 | TYMP (0.43) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL943184 | 0.78 | TYMP (0.43) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL12427908 | 0.76 | TYMP (0.44) | LMNATHRBCYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005972-A1 | Application of Staudinger Ligation in PET Imaging | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130005972-A1 | Application of Staudinger Ligation in PET Imaging | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2011123444-A1 | APPLICATION OF STAUDINGER LIGATION IN PET IMAGING | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005972-A1 | Application of Staudinger Ligation in PET Imaging | SSTR4, TIE1, STAU1 | DGAT1 2955/4885FOLH1 1226/4885LMNA 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.