Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MMP8 | P22894 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264731 | 0.92 | LMNA (0.41) | DRD2DRD4DRD3MMP2MMP9 | |
| SCHEMBL943184 | 0.88 | TYMP (0.43) | TYMPCA12CA1CA2CA9 | |
| SCHEMBL12427881 | 0.88 | TYMP (0.43) | TYMPCA12CA1CA2CA9 | |
| SCHEMBL12264736 | 0.87 | DGAT1 (0.38) | TYMPCA12CA1CA2CA9 | |
| SCHEMBL12264732 | 0.86 | LMNA (0.42) | DRD2DRD4DRD3MMP2MMP9 | |
| SCHEMBL941529 | 0.83 | LMNA (0.46) | TYMPCA12CA1CA2CA9 | |
| SCHEMBL12427963 | 0.81 | TYMP (0.43) | TYMPCA12CA1CA2CA9 | |
| SCHEMBL12427908 | 0.78 | TYMP (0.44) | TYMPCA12CA1CA2CA9 | |
| SCHEMBL12264734 | 0.77 | CYP3A4 (0.35) | FOLH1EGFRGUSB | |
| SCHEMBL941807 | 0.76 | MMP2 (0.43) | MMP2MMP9MMP8MMP13TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101921263-A | 2-metridazloe derivative as well as application and preparation method thereof | UNIV LANZHOU | 2010-12-22 | — | — | CN | disclosed |