SCHEMBL12267166

SCHEMBL12267166

Cc1cnc(-c2noc(C)n2)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 3/20 0.39
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
PLK1 P53350 1/20 0.36
HDAC4 P56524 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NR1I2 O75469 1/20 0.35
MAPT P10636 3/20 0.35
HSD17B10 Q99714 3/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
OPRK1 P41145 2/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31087981 0.81 L3MBTL1 (0.41) L3MBTL1KDM4EMAOAMAOBCA12
SCHEMBL25433199 0.81 L3MBTL1 (0.41) L3MBTL1KDM4EMAOAMAOBCA12
SCHEMBL24921515 0.79 HSD17B10 (0.40) L3MBTL1KDM4ECA12CA1CA2
SCHEMBL13406792 0.76 HDAC4 (0.32) HDAC4HDAC6
SCHEMBL17069000 0.76 L3MBTL1 (0.46) L3MBTL1KDM4EMAOAMAOBCA12
SCHEMBL9965991 0.76 NPC1 (0.54) L3MBTL1KDM4EMAPTALDH1A1NPC1
SCHEMBL14848254 0.76 CCR1 (0.54) L3MBTL1KDM4ECA12CA1CA2
SCHEMBL2644517 0.73 L3MBTL1 (0.43) L3MBTL1KDM4EMAOAMAOBCA12
SCHEMBL6669276 0.73 L3MBTL1 (0.43) L3MBTL1KDM4ECA12CA1CA2
SCHEMBL1656292 0.73 L3MBTL1 (0.43) L3MBTL1KDM4EPLK1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304554-B2 Compound, composition and thin film FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8025936-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-09-27 US disclosed
US-8025933-B2 Optical anisotropic layer FUJIFILM CORPORATION (JP) 2011-09-27 US disclosed
US-7944530-B2 Optical film, polarizing plate and liquid crystal display device including an optically anisotropic layer formed from a mixture including two or more liquid crystal compounds FUJIFILM CORPORATION (JP) 2011-05-17 US disclosed
US-7872716-B2 Optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-7871538-B2 Liquid crystal composition, retardation plate, and elliptic polarizing plate FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-7851031-B2 Optically-anisotropic film and liquid-crystal display device FUJIFILM CORPORATION (JP) 2010-12-14 US disclosed
US-20100222594-A1 Compound, composition and thin film FUJIFILM CORPORATION (JP) 2010-09-02 US disclosed
US-7763181-B2 Optical compensation film, method of producing the same, and polarizing plate and liquid crystal display device using the same FUJIFILM CORPORATION (JP) 2010-07-27 US disclosed
US-7760293-B2 Optically compensatory film and polarizing plate and liquid crystal display using same FUJIFILM CORPORATION (JP) 2010-07-20 US disclosed
US-20090091690-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-04-09 US disclosed
US-7431972-B2 Optical film, and polarizing plate and liquid crystal display device using the same FUJIFILM CORPORATION (JP) 2008-10-07 US disclosed
US-7431971-B2 Retardation plate FUJIFILM CORPORATION (JP) 2008-10-07 US disclosed
US-20080193679-A1 Optical anisotropic layer FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080186443-A1 Liquid Crystal Composition, Retardation Plate, and Elliptic Polarizing Plate FUJIFILM CORPORATION (JP) 2008-08-07 US disclosed
US-20080113112-A1 Optical Compensation Film, Method of Producing the Same, and Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-20080075892-A1 Optically-Anisotropic Film and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080064879-A1 Compound ,Composition And Thin Film FUJIFILM CORPORATION (JP) 2008-03-13 US disclosed
US-20070065601-A1 Optical film, and polarizing plate and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193679-A1 Optical anisotropic layer YBX1, YBX3, H1-2 L3MBTL1 156/4885KDM4E 2542/4885MAOA 152/4885
US-20100222594-A1 Compound, composition and thin film MATR3, Q6ZSR9, FN1 L3MBTL1 3604/4885KDM4E 2507/4885MAOA 472/4885
US-20080075892-A1 Optically-Anisotropic Film and Liquid-Crystal Display Device L1CAM, CRY1, TLN1 L3MBTL1 119/4885KDM4E 3791/4885MAOA 1625/4885
US-20080064879-A1 Compound ,Composition And Thin Film YBX1, H1-2, YBX3 L3MBTL1 724/4885KDM4E 1937/4885MAOA 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.