Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12267818 | 0.72 | MEN1 (0.41) | KMT2AALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL12686069 | 0.72 | KMT2A (0.55) | KMT2AALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL3307375 | 0.71 | KMT2A (0.48) | KMT2AALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL22734862 | 0.69 | PKM (0.59) | KMT2AALDH1A1LMNATSHRMEN1 | |
| SCHEMBL17942309 | 0.68 | LMNA (0.57) | KMT2AALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL10900999 | 0.68 | CYP2C9 (0.71) | KMT2AALDH1A1CYP2C9MEN1HTT | |
| SCHEMBL31728066 | 0.68 | LMNA (0.64) | KMT2AALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL28352130 | 0.67 | CYP2C9 (0.80) | KMT2AALDH1A1LMNAL3MBTL1CYP2C9 | |
| SCHEMBL28355402 | 0.67 | CYP2C9 (0.80) | KMT2AALDH1A1LMNAL3MBTL1CYP2C9 | |
| SCHEMBL12330052 | 0.67 | PKM (0.66) | KMT2AALDH1A1LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013171-B2 | Axially asymmetric ester compound and production method thereof | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090299076-A1 | Axially asymmetric ester compound and production method thereof | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299076-A1 | Axially asymmetric ester compound and production method thereof | SQLE, COASY, TBC1D5 | KMT2A 3160/4885ALDH1A1 3208/4885LMNA 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.