Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.79 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.79 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.79 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.79 |
| ▸ | MGLL | Q99685 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406706 | 0.89 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL12271199 | 0.84 | TRPV6 (0.59) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL12270825 | 0.82 | MAOB (0.57) | TRPV6ORAI1ORAI2ORAI3ALDH1A1 | |
| SCHEMBL2964428 | 0.82 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL17816159 | 0.82 | TSHR (0.55) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL91414 | 0.82 | TSHR (0.55) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL3275158 | 0.81 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| Bromide SCHEMBL27849066 | 0.79 | TSHR (0.52) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| Ammonia Solution, Strong SCHEMBL28559843 | 0.79 | TSHR (0.52) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL2406670 | 0.78 | TRPV6 (0.76) | TRPV6ORAI1ORAI2ORAI3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | TRPV6 4868/4885ORAI1 4605/4885ORAI2 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.