Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 6/20 | 1.00 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 1.00 |
| ▸ | ORAI2 | Q96SN7 | 5/20 | 1.00 |
| ▸ | ORAI3 | Q9BRQ5 | 5/20 | 1.00 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | LPL | P06858 | 1/20 | 0.68 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266144 | 0.89 | TRPV6 (0.80) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL12271059 | 0.89 | ORAI1 (0.80) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL12266162 | 0.83 | ORAI1 (0.70) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL12270827 | 0.83 | ORAI1 (0.70) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL12270441 | 0.82 | TRPV6 (0.79) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| Tolyl Boronic Acid SCHEMBL5600068 | 0.81 | CA2 (1.00) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| Tolyl Boronic Acid SCHEMBL129197 | 0.81 | CA2 (1.00) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL5586183 | 0.80 | ORAI1 (0.67) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL2399139 | 0.80 | ORAI1 (0.64) | TRPV6ORAI1ORAI2ORAI3CA2 | |
| SCHEMBL12266213 | 0.80 | TRPV6 (0.64) | TRPV6ORAI1ORAI2ORAI3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620905-A1 | ELECTROLUMINESCENT BORON COMPLEXES | NUKO 70 Limited (GB) | 2006-02-01 | — | — | EP | claimed |
| WO-2004084325-A1 | ELECTROLUMINESCENT BORON COMPLEXES | NUKO 70 LIMITED (GB) | 2004-09-30 | — | — | WO | claimed |
| EP-1140947-B1 | METHOD FOR PRODUCING MONO-ORGANOBORANES OR DI-ORGANOBORANES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | claimed |
| US-20260050210-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING SAME | NIPPON SHOKUBAI CO., LTD. (JP) | 2026-02-19 | — | — | US | disclosed |
| WO-2024122460-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING SAME | 株式会社日本触媒 | 2024-06-13 | — | — | WO | disclosed |
| US-10570157-B2 | Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors | THE UNIVERSITY OF MANCHESTER (GB) | 2020-02-25 | — | — | US | disclosed |
| US-10570157-B2 | Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors | THE UNIVERSITY OF MANCHESTER (GB) | 2020-02-25 | — | — | US | disclosed |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | THE UNIVERSITY OF MANCHESTER (GB) | 2018-08-02 | — | — | US | disclosed |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | THE UNIVERSITY OF MANCHESTER (GB) | 2018-08-02 | — | — | US | disclosed |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | THE UNIVERSITY OF MANCHESTER (GB) | 2018-08-02 | — | — | US | disclosed |
| EP-3328868-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | The University of Manchester (GB) | 2018-06-06 | — | — | EP | disclosed |
| US-6500951-B1 | RING CLOSING A CARBOXYLIC ACID DERIVATIVE IN PRESENCE OF A NITROGEN CONTAINING AROMATIC COMPOUND AND A BORON COMPOUND; HIGH YIELD AND PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-31 | — | — | US | disclosed |
| US-20020161230-A1 | Process for preparing boronic and borinic acids | CLARIANT GMBH | 2002-10-31 | — | — | US | disclosed |
| EP-1236730-A2 | Process for preparing boronic and borinic acids | Clariant GmbH (DE) | 2002-09-04 | — | — | EP | disclosed |
| US-6417302-B1 | REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2002-07-09 | — | — | US | disclosed |
| EP-1137641-A1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034249-A1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-15 | — | — | WO | disclosed |
| EP-1003753-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | Basell Polyolefine GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006414-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | TARGOR GMBH (DE) | 1999-02-11 | — | — | WO | disclosed |
| US-4713346-A | Formation of analyzable boron containing adducts | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570157-B2 | Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors | NLRP3, IL1B, NOD1 | TRPV6 675/4885ORAI1 736/4885ORAI2 1793/4885 |
| US-20020161230-A1 | Process for preparing boronic and borinic acids | BZW1, CYP2W1, BZW2 | TRPV6 1935/4885ORAI1 2892/4885ORAI2 822/4885 |
| US-20260050210-A1 | RESIST COMPOSITION AND METHOD FOR PRODUCING SAME | MAL2, MCM6, MCM3 | TRPV6 2089/4885ORAI1 505/4885ORAI2 712/4885 |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | NLRP3, IL1B, NOD1 | TRPV6 675/4885ORAI1 736/4885ORAI2 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.