Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.54 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidino Acetate SCHEMBL28705265 | 0.90 | EGLN1 (0.43) | EGLN1MAPK1SLC13A3OR51E2LMNA | |
| Guanidino Acetate SCHEMBL33970 | 0.83 | — | — | |
| Guanidino Acetate SCHEMBL27413696 | 0.83 | EGLN1 (0.41) | EGLN1LMNAKDM4EPLA2G2ACA1 | |
| Alpha-Ketoglutaric Acid SCHEMBL30862136 | 0.82 | EGLN1 (0.61) | EGLN1MAPK1SLC13A3OR51E2LMNA | |
| Guanidino Acetate SCHEMBL3331092 | 0.81 | — | — | |
| Guanidino Acetate SCHEMBL31316639 | 0.81 | — | — | |
| Guanidino Acetate SCHEMBL20531119 | 0.81 | — | — | |
| Guanidino Acetate SCHEMBL29087529 | 0.81 | — | — | |
| Guanidino Acetate SCHEMBL1098127 | 0.81 | — | — | |
| Guanidino Acetate SCHEMBL19458353 | 0.81 | EGLN1 (0.39) | EGLN1LMNAKDM4EPLA2G2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536222-B2 | Addition compounds of guanidinoacetic acid | ALZCHEM AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-20120238629-A1 | ADDITION COMPOUNDS OF GUANIDINOACETIC ACID | ALZCHEM TROSTBERG GMBH (DE) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238629-A1 | ADDITION COMPOUNDS OF GUANIDINOACETIC ACID | GCDH, PCCA, PC | EGLN1 2586/4885MAPK1 3155/4885SLC13A3 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.