Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12279466 | 0.88 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2C9 | |
| SCHEMBL12279439 | 0.83 | CYP2A6 (0.54) | CYP19A1CYP2A6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL26847613 | 0.77 | CYP19A1 (0.45) | CYP19A1ALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL24419697 | 0.74 | POLB (0.47) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2C9 | |
| SCHEMBL27114058 | 0.73 | PKM (0.49) | CYP2A6CYP2C9CYP2C19CYP3A4CYP2E1 | |
| SCHEMBL28049612 | 0.73 | CYP2A6 (0.57) | CYP2A6CYP2C9CYP2C19CYP3A4CYP2E1 | |
| SCHEMBL12279420 | 0.72 | CYP2A6 (0.46) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2C9 | |
| SCHEMBL24419798 | 0.71 | FYN (0.43) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2C9 | |
| SCHEMBL12278118 | 0.71 | CYP2A6 (0.44) | CYP19A1CYP2A6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL17375118 | 0.71 | FAAH (0.52) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-2586312-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| US-8809547-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-19 | — | — | US | disclosed |
| US-8809547-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-19 | — | — | US | disclosed |
| EP-2591674-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-15 | — | — | EP | disclosed |
| EP-2586312-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586311-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP19A1 273/4885CYP11B1 129/4885CYP11B2 119/4885 |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP19A1 273/4885CYP11B1 129/4885CYP11B2 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.