SCHEMBL12280200

SCHEMBL12280200

COCC1O[C@@H](O)C(NC(C)=O)[C@@H](O)[C@@H]1OC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.46
▸ LGALS3 P17931 5/20 0.41
▸ LGALS8 O00214 1/20 0.36
▸ LGALS4 P56470 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ LGALS1 P09382 1/20 0.34
▸ LGALS7; LGALS7B P47929 1/20 0.34
▸ NOD2 Q9HC29 1/20 0.34
▸ AMDHD2 Q9Y303 1/20 0.33
▸ CD69 Q07108 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7154489 0.87 LGALS3 (0.44) MAPK1LGALS3LGALS8LGALS4ALDH1A1
SCHEMBL7155174 0.87 LGALS3 (0.44) MAPK1LGALS3LGALS8LGALS4ALDH1A1
SCHEMBL25043094 0.87 MAPK1 (0.56) MAPK1LGALS3LGALS8LGALS4ALDH1A1
SCHEMBL13491439 0.87 MAPK1 (0.56) MAPK1LGALS3LGALS8LGALS4ALDH1A1
SCHEMBL7591374 0.87 MAPK1 (0.56) MAPK1LGALS3LGALS8LGALS4ALDH1A1
SCHEMBL13308281 0.87 MAPK1 (0.56) MAPK1LGALS3LGALS8LGALS4ALDH1A1
SCHEMBL18391246 0.86 MAPK1 (0.49) MAPK1LGALS3ALDH1A1THRBKMT2A
SCHEMBL26229737 0.86 MAPK1 (0.49) MAPK1LGALS3ALDH1A1THRBKMT2A
SCHEMBL13240509 0.86 MAPK1 (0.49) MAPK1LGALS3ALDH1A1THRBKMT2A
SCHEMBL4314010 0.86 MAPK1 (0.49) MAPK1LGALS3ALDH1A1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9933432-B2 Multi-dimensional chromatographic methods for separating N-glycans MOMENTA PHARMACEUTICALS, INC. (US) 2018-04-03 — — US disclosed
US-20170212129-A1 MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS MOMENTA PHARMACEUTICALS, INC. 2017-07-27 — — US disclosed
US-20160356783-A1 MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS MOMENTA PHARMACEUTICALS, INC. 2016-12-08 — — US disclosed
US-9448147-B2 Multi-dimensional chromatographic methods for separating N-glycans MOMENTA PHARMACEUTICALS, INC. (US) 2016-09-20 — — US disclosed
US-8703498-B2 Multi-dimensional chromatographic methods for separating N-glycans MOMENTA PHARMACEUTICALS, INC. (US) 2014-04-22 — — US disclosed
US-20140065716-A1 MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS MOMENTA PHARMACEUTICALS, INC. (US) 2014-03-06 — — US disclosed
US-20130029365-A1 MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS MOMENTA PHARMACEUTICALS, INC. (US) 2013-01-31 — — US disclosed
US-8304250-B2 Multi-dimensional chromatographic methods for separating N-glycans MOMENTA PHARMACEUTICALS, INC. (US) 2012-11-06 — — US disclosed
US-20110213137-A1 ISOTOPICALLY-LABELED GLYCANS MOMENTA PHARMACEUTICALS, INC. (US) 2011-09-01 — — US disclosed
US-20100151584-A1 MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS MOMENTA PHARMACEUTICALS, INC. (US) 2010-06-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110213137-A1 ISOTOPICALLY-LABELED GLYCANS FUT5, FUT6, ST3GAL3 MAPK1 4093/4885LGALS3 51/4885LGALS8 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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