Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 19/20 | 0.72 |
| ▸ | MEN1 | O00255 | 17/20 | 0.72 |
| ▸ | MAPT | P10636 | 12/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 14/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 12/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14681431 | 0.84 | KMT2A (1.00) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL12282406 | 0.80 | KMT2A (0.62) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL12280667 | 0.78 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL12281283 | 0.77 | KMT2A (0.76) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL12280979 | 0.77 | KMT2A (0.74) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL27952547 | 0.75 | KMT2A (0.58) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL16872924 | 0.75 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL15078624 | 0.73 | KMT2A (0.65) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL12281794 | 0.72 | KMT2A (0.73) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL30209644 | 0.72 | KMT2A (0.60) | KMT2AMEN1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011127192-A2 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2011-10-13 | — | — | WO | disclosed |