Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.65 |
| ▸ | MEN1 | O00255 | 12/20 | 0.65 |
| ▸ | NPC1 | O15118 | 11/20 | 0.65 |
| ▸ | RAB9A | P51151 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283434 | 0.84 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL3859264 | 0.82 | KMT2A (0.70) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL27952547 | 0.80 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL28662218 | 0.79 | KMT2A (0.50) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL12281794 | 0.77 | KMT2A (0.73) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL28555834 | 0.77 | CYP1A2 (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL15532332 | 0.77 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL12280667 | 0.76 | KMT2A (0.66) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL4458654 | 0.76 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL19603065 | 0.76 | KMT2A (0.50) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364454-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-12-11 | — | — | US | disclosed |
| US-20140364454-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-12-11 | — | — | US | disclosed |
| WO-2013092556-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | UNIVERSITE DE RENNES I (FR) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364454-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | SLC30A7, HAMP, SLC8B1 | KMT2A 523/4885MEN1 1464/4885NPC1 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.