SCHEMBL1228215

SCHEMBL1228215

CC[SiH](CC)CCCC(=O)C(C)(C)Br

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16921211 0.78 FAAH (0.37) FAAHCES1CES2MEN1CYP1A2
SCHEMBL6514015 0.73 FAAH (0.32) FAAHCES1CES2MEN1CYP1A2
SCHEMBL12285742 0.72 GPR84 (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL3793062 0.68
SCHEMBL19391043 0.68 FAAH (0.36) FAAHCES1CES2MEN1CYP1A2
SCHEMBL24383617 0.67 FAAH (0.30) FAAH
SCHEMBL13336566 0.67 FAAH (0.34) FAAHCES1CES2MEN1CYP1A2
SCHEMBL5314831 0.67 LMNA (0.31)
SCHEMBL13336569 0.65 FAAH (0.36) FAAHCES1CES2MEN1CYP1A2
SCHEMBL4029336 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011106302-A1 SYNTHETIC PEPTIDE (METH) ACRYLATE MICROCARRIERS CORNING INCORPORATED (US) 2011-09-01 WO claimed
US-20110207216-A1 Synthetic Peptide (Meth) Acrylate Microcarriers CORNING INCORPORATED 2011-08-25 US claimed
US-8404485-B2 Synthetic microcarriers for culturing cells CORNING INCORPORATED (US) 2013-03-26 US disclosed
US-20120288912-A1 SYNTHETIC MICROCARRIERS FOR CULTURING CELLS MCCARTHY KEVIN ROBERT (US) 2012-11-15 US disclosed
US-8257828-B2 Synthetic microcarriers for culturing cells CORNING INCORPORATED (US) 2012-09-04 US disclosed
EP-2459701-A1 SYNTHETIC MICROCARRIERS FOR CULTURING CELLS Corning Inc. (US) 2012-06-06 EP disclosed
WO-2011106302-A1 SYNTHETIC PEPTIDE (METH) ACRYLATE MICROCARRIERS CORNING INCORPORATED (US) 2011-09-01 WO disclosed
US-20110207216-A1 Synthetic Peptide (Meth) Acrylate Microcarriers CORNING INCORPORATED 2011-08-25 US disclosed
WO-2011017050-A1 SYNTHETIC MICROCARRIERS FOR CULTURING CELLS CORNING INCORPORATED (US) 2011-02-10 WO disclosed
US-20110027889-A1 Synthetic Microcarriers for Culturing Cells CORNING INCORPORATED 2011-02-03 US disclosed