SCHEMBL804880

SCHEMBL804880

CCCCCCn1c2ccc(C)cc2c2cc(C)ccc21

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RORA P35398 3/20 0.61
RORC P51449 3/20 0.61
RORB Q92753 3/20 0.61
PGR P06401 1/20 0.61
TLR8 Q9NR97 2/20 0.55
PSEN1 P49768 5/20 0.54
PSEN2 P49810 5/20 0.54
APH1B Q8WW43 5/20 0.54
NCSTN Q92542 5/20 0.54
APH1A Q96BI3 5/20 0.54
PSENEN Q9NZ42 5/20 0.54
CNR2 P34972 8/20 0.49
SIRT2 Q8IXJ6 2/20 0.46
SIRT1 Q96EB6 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14261677 1.00 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL12284774 1.00 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL12593202 1.00 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL13503151 1.00 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL15396934 1.00 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL12593203 0.98 RORA (0.63) RORARORCRORBPGRTLR8
SCHEMBL13125230 0.97 RORA (0.58) RORARORCRORBPGRTLR8
SCHEMBL6365787 0.94 RORA (0.56) RORARORCRORBPGRTLR8
SCHEMBL14029768 0.94 PGR (0.56) RORARORCRORBPGRTLR8
SCHEMBL12374352 0.93 RORA (0.69) RORARORCRORBPGRTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783554-B2 Lanthanide ion complexes and imaging method THE UNIVERSITY OF AKRON (US) 2017-10-10 US disclosed
US-9783554-B2 Lanthanide ion complexes and imaging method THE UNIVERSITY OF AKRON (US) 2017-10-10 US disclosed
US-20170253795-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-07 US disclosed
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed
US-20160333028-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON 2016-11-17 US disclosed
US-20160333028-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON 2016-11-17 US disclosed
US-8143465-B2 Soluble branched triaroylbenzene-based polymer and its synthetic method THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) 2012-03-27 US disclosed
US-8143465-B2 Soluble branched triaroylbenzene-based polymer and its synthetic method THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) 2012-03-27 US disclosed
US-20120070378-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON (US) 2012-03-22 US disclosed
US-20120070378-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON (US) 2012-03-22 US disclosed
US-20110121278-A1 SOLUTION COMPOSITION AND POLYMER LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL CO., LTD. (JP) 2011-05-26 US disclosed
US-7910025-B2 Solution composition and polymer light-emitting device SUMITOMO CHEMICAL CO., LTD. (JP) 2011-03-22 US disclosed
US-7659353-B2 Hyperbranched polymers THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-02-09 US disclosed
US-20080061673-A1 Solution Composition And Polymer Light-Emitting Device SUMITOMO CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160333028-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD HRH3, KCNH3, RXFP3 RORA 2558/4885RORC 3175/4885RORB 2919/4885
US-20120070378-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD INSR, KCNH3, CA9 RORA 2582/4885RORC 2852/4885RORB 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.