Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306556 | 1.00 | PRMT3 (0.38) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25075403 | 0.95 | EPHX1 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25075399 | 0.95 | EPHX1 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL3076001 | 0.93 | EPHX1 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL16256663 | 0.91 | EPHX1 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL903463 | 0.89 | EPHX1 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL15569827 | 0.89 | PRMT3 (0.45) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL3317331 | 0.88 | CYP1A2 (0.45) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL8305883 | 0.86 | PRMT3 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trolamine SCHEMBL4857518 | 0.86 | PRMT3 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125589-A1 | LIPIDOID COMPOSITIONS AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2022-06-16 | — | — | WO | disclosed |
| EP-2571973-B1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2020-04-01 | — | — | EP | disclosed |
| WO-2019150138-A1 | CONJUGATES OF CYCLODEXTRINS AND DEFERASIROX OR ANALOGUES THEREOF | THE UNIVERSITY OF SUSSEX (GB) | 2019-08-08 | — | — | WO | disclosed |
| US-9150753-B2 | Method for making waterborne polyurethane with a reactive functional group and a nanocomposite made of the same | NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) | 2015-10-06 | — | — | US | disclosed |
| US-9150753-B2 | Method for making waterborne polyurethane with a reactive functional group and a nanocomposite made of the same | NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) | 2015-10-06 | — | — | US | disclosed |
| US-9018151-B2 | Optical brighteners and compositions comprising the same | MILLIKEN & COMPANY (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140343224-A1 | Method for Making Waterborne Polyurethane with a Reactive Functional Group and a Nanocomposite Made of the Same | NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) | 2014-11-20 | — | — | US | disclosed |
| US-20140343224-A1 | Method for Making Waterborne Polyurethane with a Reactive Functional Group and a Nanocomposite Made of the Same | NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) | 2014-11-20 | — | — | US | disclosed |
| US-8740997-B2 | Optical brighteners and compositions comprising the same | MILLIKEN & COMPANY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130281347-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY | 2013-10-24 | — | — | US | disclosed |
| US-8454711-B2 | Optical brighteners and compositions comprising the same | MILLIKEN & COMPANY (US) | 2013-06-04 | — | — | US | disclosed |
| WO-2011104334-A1 | 4 - [CYCLOALKYLOXY (HETERO) ARYLAMINO] THIENO [2, 3 - D] PYRIMIDINES HAVING MNKL/ MNK2 INHIBITING ACTIVITY FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-01 | — | — | WO | disclosed |
| US-7956060-B2 | Pyrimidine derivative compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-7956060-B2 | Pyrimidine derivative compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| US-7524852-B2 | Bicyclic pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524852-B2 | Bicyclic pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7183409-B2 | Basic mono- and bisazo compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-02-27 | — | — | US | disclosed |
| US-7183409-B2 | Basic mono- and bisazo compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | UROD, UTS2R, SLC14A1 | PRMT3 378/4885CARM1 520/4885PRMT6 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.