Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 19/20 | 0.50 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966575 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL14966618 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL12291653 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL2409077 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL2409863 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL12320495 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL2410171 | 0.87 | TRPC6 (0.52) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL2411532 | 0.85 | SLC9A3 (0.50) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL2408231 | 0.85 | SLC9A3 (0.50) | SLC9A3TRPC6CYP2D6 | |
| SCHEMBL12363441 | 0.82 | TRPC6 (0.47) | SLC9A3TRPC6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |