Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.52 |
| ▸ | SLC9A3 | P48764 | 19/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966575 | 1.00 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL2409077 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL2409863 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL12291653 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL2410171 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL12320495 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL12320194 | 0.87 | SLC9A3 (0.50) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL12363441 | 0.86 | TRPC6 (0.47) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL2411532 | 0.85 | SLC9A3 (0.50) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL2408231 | 0.85 | SLC9A3 (0.50) | TRPC6SLC9A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | ANXA2, ANXA3, ADM2 | TRPC6 3080/4885SLC9A3 1898/4885CYP2D6 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.