Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015993 | 0.83 | FTO (0.33) | KDM4CCA12CA1CA2CA9 | |
| SCHEMBL12779403 | 0.81 | RAB9A (0.34) | CA9ALDH1A1ALOX5PTGS2HTT | |
| SCHEMBL17917406 | 0.80 | FTO (0.48) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL14600031 | 0.77 | CA12 (0.31) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12678084 | 0.76 | HSD17B10 (0.38) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL19543327 | 0.76 | HSP90AB1 (0.35) | HPGDALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL14620246 | 0.75 | HSD17B10 (0.39) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL12926177 | 0.74 | MEN1 (0.53) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL12171475 | 0.73 | MEN1 (0.39) | CA12CA1CA9KMT2AMEN1 | |
| SCHEMBL19543149 | 0.73 | HSD17B10 (0.36) | GAAKMT2ARECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106639-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2011-09-01 | — | — | WO | disclosed |