Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 6/20 | 0.31 |
| ▸ | CA2 | P00918 | 6/20 | 0.31 |
| ▸ | CA9 | Q16790 | 6/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917406 | 0.84 | FTO (0.48) | FTOHSD17B10MEN1USP2POLB | |
| SCHEMBL12291666 | 0.83 | KDM4C (0.40) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL19749039 | 0.82 | HSD17B10 (0.35) | HSD17B10MEN1USP2POLBHSP90AA1 | |
| SCHEMBL12171475 | 0.81 | MEN1 (0.39) | HSD17B10MEN1USP2POLBHSP90AA1 | |
| SCHEMBL12678084 | 0.80 | HSD17B10 (0.38) | HSD17B10MEN1USP2POLBHSP90AA1 | |
| SCHEMBL14620246 | 0.79 | HSD17B10 (0.39) | HSD17B10MEN1USP2POLBHSP90AA1 | |
| SCHEMBL12926177 | 0.78 | MEN1 (0.53) | FTOHSD17B10MEN1USP2POLB | |
| SCHEMBL19749041 | 0.77 | MEN1 (0.37) | HSD17B10MEN1USP2POLBHSP90AA1 | |
| SCHEMBL19543149 | 0.77 | HSD17B10 (0.36) | HSD17B10MEN1USP2POLBHSP90AA1 | |
| SCHEMBL17930252 | 0.77 | MEN1 (0.39) | HSD17B10MEN1USP2POLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889213-B2 | Multimodal imaging of fibrin | THE GENERAL HOSPITAL CORPORATION (US) | 2018-02-13 | — | — | US | disclosed |
| US-20160199519-A1 | Multimodal Imaging of Fibrin | THE GENERAL HOSPITAL CORPORATION | 2016-07-14 | — | — | US | disclosed |
| US-9200017-B2 | Multimodal imaging of fibrin | THE GENERAL HOSPITAL CORPORATION (US) | 2015-12-01 | — | — | US | disclosed |
| US-20120077958-A1 | Multimodal Imaging of Fibrin | THE GENERAL HOSPITAL CORPORATION | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077958-A1 | Multimodal Imaging of Fibrin | FGB, F2, SERPINC1 | FTO 2886/4885HSD17B10 3821/4885MEN1 605/4885 |
| US-20160199519-A1 | Multimodal Imaging of Fibrin | FGB, F2, SERPINC1 | FTO 2886/4885HSD17B10 3821/4885MEN1 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.