Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214393 | 0.88 | GSTP1 (0.56) | CA12CA9CA4CA1CA2 | |
| SCHEMBL5704167 | 0.83 | CA12 (0.63) | CA12CA9CA4CA1CA2 | |
| SCHEMBL7743518 | 0.80 | MAOB (0.46) | CA12CA9CA4CA1CA2 | |
| Hydrochloric Acid SCHEMBL21694040 | 0.80 | CA12 (0.61) | CA12CA9CA4CA1CA2 | |
| SCHEMBL919633 | 0.80 | GAA (0.38) | CA12CA9CA4CA1CA2 | |
| SCHEMBL22494 | 0.79 | SYK (0.37) | CA12CA9CA1MAOBPOLB | |
| SCHEMBL920034 | 0.78 | MAOB (0.44) | CA12CA9CA4CA1CA2 | |
| SCHEMBL920287 | 0.77 | MAOB (0.45) | CA12CA9CA4CA1CA2 | |
| SCHEMBL72587 | 0.76 | MAOB (0.56) | CA12CA9CA4CA1CA2 | |
| SCHEMBL15800551 | 0.76 | CA12 (0.57) | CA12CA9CA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557926-B | Squaraine compound and preparation method and application thereof | 深圳大学 | 2024-02-06 | — | — | CN | claimed |
| EP-3745505-B1 | FUNCTIONALIZED LITHIUM ANODE FOR BATTERIES | ACONDICIONAMIENTO TARRASENSE (ES) | 2023-11-29 | — | — | EP | claimed |
| CN-116462616-A | Alkynylamide compounds and application thereof | 暨南大学 | 2023-07-21 | — | — | CN | claimed |
| CN-114436919-B | Alpha-difluoro sulfur methyl ketone (alcohol) derivative and synthetic method thereof | 华南理工大学 | 2023-01-06 | — | — | CN | claimed |
| CN-115557926-A | Squarylium cyanine compound and preparation method and application thereof | 深圳大学 | 2023-01-03 | — | — | CN | claimed |
| CN-114436919-A | Alpha-difluoro sulfur methyl ketone (alcohol) derivative and synthetic method thereof | 华南理工大学 | 2022-05-06 | — | — | CN | claimed |
| EP-3197277-B1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION INC (US) | 2021-12-22 | — | — | EP | claimed |
| CN-109704638-B | Brake lining for automobile | 桐庐宇鑫汽配有限公司 | 2021-03-26 | — | — | CN | claimed |
| EP-2915186-B1 | FORMULATIONS OF SOLUTIONS AND PROCESSES FOR FORMING A SUBSTRATE INCLUDING AN ARSENIC DOPANT | VERSUM MAT US LLC (US) | 2020-10-28 | — | — | EP | claimed |
| US-20170283439-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CCHDI Foundation Inc. (US) | 2017-10-05 | — | — | US | claimed |
| EP-2516426-B1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-09-16 | — | — | EP | claimed |
| US-20140057945-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-27 | — | — | US | claimed |
| US-8524743-B2 | Bis(difluoromethyl)pyrazoles as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-09-03 | — | — | US | claimed |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-09-15 | — | — | US | claimed |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | claimed |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | EFREMOV IVAN | 2008-11-13 | — | — | US | claimed |
| WO-2008012623-A1 | BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008012622-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-0621864-B1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | claimed |
| WO-1993008183-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES | CIBA-GEIGY AG (CH) | 1993-04-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | PAICS, TMBIM6, ABCG2 | CA12 3166/4885CA9 1382/4885CA4 1508/4885 |
| US-20170283439-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | CA12 2572/4885CA9 3467/4885CA4 3748/4885 |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | CA12 1750/4885CA9 799/4885CA4 1060/4885 |
| US-20110224257-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP1A1, CYP4X1, CYP2F1 | CA12 4328/4885CA9 2220/4885CA4 1987/4885 |
| US-20140057945-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP1A1, CYP4X1, CYP2F1 | CA12 4328/4885CA9 2220/4885CA4 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.