Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12290960 | 0.83 | ERN1 (0.49) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL16528202 | 0.79 | ERN1 (0.47) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL16359749 | 0.77 | ERN1 (0.42) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL12291055 | 0.74 | SLC6A4 (0.35) | ALDH1A1POLB | |
| SCHEMBL4439253 | 0.73 | ERN1 (0.45) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL1017248 | 0.73 | ERN1 (0.52) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL31050324 | 0.73 | ERN1 (0.52) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL7248576 | 0.71 | ALDH1A1 (0.43) | ERN1PTGDR2ALDH1A1POLBLMNA | |
| SCHEMBL203395 | 0.69 | ERN1 (0.61) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 | |
| SCHEMBL1145175 | 0.69 | ERN1 (0.47) | ERN1PTGDR2CYP2A6PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107494-A1 | NOVEL AROMATIC GLYCOSIDE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND THE USE THEREOF | SANOFI (FR) | 2011-09-09 | — | — | WO | disclosed |