Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094734 | 0.84 | GAA (0.67) | CYP1A1CYP1A2CYP1B1GAACTSS | |
| SCHEMBL6238615 | 0.82 | GAA (0.69) | CYP1A1CYP1B1GAARECQL | |
| SCHEMBL12775962 | 0.81 | CTSS (0.46) | CYP1A1CYP1A2CYP1B1GAACTSS | |
| SCHEMBL12868318 | 0.80 | ATP4A (0.55) | IDO1SIRT5TSHRRECQL | |
| SCHEMBL1858562 | 0.79 | EIF4E (0.61) | CYP1A1CYP1A2CYP1B1GAAIDO1 | |
| SCHEMBL30552612 | 0.79 | ALDH1A1 (0.59) | CYP1A1CYP1A2CYP1B1IDO1CLK4 | |
| SCHEMBL7371077 | 0.79 | ALDH1A1 (0.59) | CYP1A1CYP1A2CYP1B1IDO1CLK4 | |
| SCHEMBL3765637 | 0.79 | IDO1 (0.49) | CYP1A1CYP1A2CYP1B1GAACTSS | |
| Bromide SCHEMBL30552479 | 0.78 | ALDH1A1 (0.60) | CYP1A1CYP1A2CYP1B1IDO1CLK4 | |
| Bromide SCHEMBL29056835 | 0.78 | ALDH1A1 (0.60) | CYP1A1CYP1A2CYP1B1IDO1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224231-A1 | Novel Lactams as Beta Secretase Inhibitors | PFIZER INC. (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224231-A1 | Novel Lactams as Beta Secretase Inhibitors | BACE1, BACE2, APH1B | CYP1A1 2092/4885CYP1A2 1979/4885CYP1B1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.