Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 5/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12458573 | 0.88 | ME2 (0.59) | SLC6A7GPR119KDM4EP4HTMGRM5 | |
| SCHEMBL21551042 | 0.87 | SLC6A7 (0.62) | SLC6A7GPR119KDM4EALKBH1P4HTM | |
| SCHEMBL2370403 | 0.85 | SLC6A7 (0.55) | SLC6A7GPR119KDM4EALKBH1P4HTM | |
| SCHEMBL21551627 | 0.83 | SLC6A7 (0.58) | SLC6A7GPR119KDM4EALKBH1P4HTM | |
| Hydrochloric Acid SCHEMBL2309495 | 0.81 | ME2 (0.58) | SLC6A7KDM4EGRM5ME2ME1 | |
| SCHEMBL12740686 | 0.80 | GPR119 (0.82) | SLC6A7GPR119 | |
| SCHEMBL12820445 | 0.79 | GPR119 (0.58) | SLC6A7GPR119KDM4EALKBH1P4HTM | |
| SCHEMBL12293991 | 0.79 | GPR119 (0.60) | SLC6A7GPR119SIGMAR1 | |
| SCHEMBL15952657 | 0.79 | KIT (0.54) | SLC6A7GPR119ALKBH1P4HTMKIT | |
| SCHEMBL20475489 | 0.78 | NPC1 (0.60) | SLC6A7KDM4EALKBH1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110488-A1 | A NOVEL PET IMAGING AGENT OF AMYLOID PLAQUES AND ITS PRECURSOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-09-15 | — | — | WO | disclosed |