SCHEMBL12295397

SCHEMBL12295397

Brc1ccc2c(Cc3ccccc3)c(Br)ccc2c1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.48
ALDH1A1 P00352 3/20 0.39
TRPA1 O75762 1/20 0.39
TSHR P16473 1/20 0.39
CTRC Q99895 1/20 0.36
NQO1 P15559 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BCL2 P10415 1/20 0.35
BCL2L1 Q07817 1/20 0.35
TYMP P19971 1/20 0.35
SHBG P04278 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
LTA4H P09960 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1841464 0.78 CALM1 (0.61) CALM1ALDH1A1TRPA1TSHRNQO1
SCHEMBL16054535 0.77 CALM1 (0.42) CALM1ALDH1A1TRPA1TSHRCTRC
SCHEMBL27277755 0.77 IDH1 (0.45) CALM1ALDH1A1TRPA1TSHRNQO1
SCHEMBL593991 0.75 CALM1 (0.41) CALM1ALDH1A1TRPA1TSHRMEN1
SCHEMBL2820256 0.74 CALM1 (0.73) CALM1ALDH1A1TRPA1TSHRKDM4E
SCHEMBL7669757 0.74 CALM1 (0.44) CALM1ALDH1A1TRPA1TSHRKDM4E
SCHEMBL29029452 0.72 ALDH1A1 (0.40) CALM1ALDH1A1TRPA1TSHRCTRC
SCHEMBL7632931 0.72 BCL2 (0.45) CALM1BCL2BCL2L1MEN1KMT2A
SCHEMBL27286175 0.72 ALDH1A1 (0.48) CALM1ALDH1A1CTRCNQO1TDP1
SCHEMBL29029437 0.71 TSHR (0.39) CALM1TSHRTDP1BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2368892-A1 NOVEL COMPOUND, PROCESS FOR PRODUCING THE COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE Hiroshima University (JP) 2011-09-28 EP disclosed