Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029452 | 0.84 | ALDH1A1 (0.40) | TSHRCALM1LTA4HRAB9ASMN1; SMN2 | |
| SCHEMBL7669757 | 0.80 | CALM1 (0.44) | TSHRCALM1LTA4HRAB9ASMN1; SMN2 | |
| SCHEMBL27507868 | 0.76 | ESR1 (0.36) | CALM1 | |
| SCHEMBL12295397 | 0.71 | CALM1 (0.48) | TSHRCALM1LTA4HBCL2BCL2L1 | |
| SCHEMBL16054535 | 0.71 | CALM1 (0.42) | TSHRCALM1L3MBTL1MEN1KMT2A | |
| SCHEMBL27277755 | 0.71 | IDH1 (0.45) | TSHRCALM1LTA4H | |
| SCHEMBL27674533 | 0.69 | EPAS1 (0.36) | CALM1L3MBTL1 | |
| SCHEMBL1204710 | 0.68 | CALM1 (0.44) | CALM1SMN1; SMN2BCL2BCL2L1 | |
| SCHEMBL28417332 | 0.67 | DRD4 (0.39) | TSHR | |
| SCHEMBL7632931 | 0.67 | BCL2 (0.45) | CALM1BCL2BCL2L1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661387-B | Composition for treating pulmonary fibrosis | 维克图斯生物系统有限公司 | 2023-05-30 | — | — | CN | disclosed |