Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471594 | 0.89 | ALDH1A1 (0.33) | — | |
| SCHEMBL28900909 | 0.89 | ALDH1A1 (0.33) | — | |
| SCHEMBL28484647 | 0.86 | BLM (0.30) | — | |
| SCHEMBL27093071 | 0.86 | BLM (0.30) | — | |
| SCHEMBL3796353 | 0.86 | ZDHHC20 (0.43) | ZDHHC20MEN1THRBHTTKMT2A | |
| SCHEMBL3871697 | 0.86 | BLM (0.30) | — | |
| SCHEMBL7061683 | 0.84 | CA12 (0.40) | HTTMAPT | |
| SCHEMBL28036839 | 0.81 | CA12 (0.34) | — | |
| SCHEMBL4359796 | 0.81 | CA12 (0.31) | — | |
| SCHEMBL16367157 | 0.78 | HTT (0.50) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039990-A1 | REACTIVE SURFACE-MODIFIED PARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2011-02-17 | — | — | US | disclosed |