Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229787 | 0.86 | ZDHHC20 (0.41) | ZDHHC20CES2MEN1THRBHTT | |
| SCHEMBL28036930 | 0.82 | LMNA (0.36) | LMNALPAR1LPAR5 | |
| SCHEMBL9194761 | 0.82 | LMNA (0.32) | LMNA | |
| SCHEMBL5933149 | 0.78 | TSHR (0.46) | ZDHHC20CES2MEN1THRBHTT | |
| SCHEMBL29837976 | 0.78 | LMNA (0.39) | ZDHHC20LMNACES2MEN1THRB | |
| SCHEMBL3844670 | 0.77 | CA12 (0.36) | LMNAMAPT | |
| SCHEMBL9452183 | 0.77 | LMNA (0.32) | LMNA | |
| SCHEMBL23152406 | 0.77 | LMNA (0.55) | LMNACES2MEN1THRBHTT | |
| SCHEMBL6559383 | 0.77 | LMNA (0.55) | LMNACES2MEN1THRBHTT | |
| SCHEMBL16608923 | 0.76 | CES2 (0.47) | ZDHHC20LMNACES2MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100092761-A1 | NANOPARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-04-15 | — | — | US | disclosed |