SCHEMBL1229928

SCHEMBL1229928

CCCCc1ccc(NN)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.51
POLB P06746 1/20 0.51
CA2 P00918 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HTR2A P28223 1/20 0.50
CA1 P00915 2/20 0.49
CA12 O43570 1/20 0.49
CA9 Q16790 1/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.47
PLK1 P53350 1/20 0.47
HSD17B10 Q99714 1/20 0.47
F13A1 P00488 1/20 0.46
TGM2 P21980 1/20 0.46
SPHK1 Q9NYA1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28377539 0.98 HPGD (0.50) HPGDPOLBCA2SMN1; SMN2HTR2A
Hydrochloric Acid SCHEMBL1723029 0.98 HPGD (0.50) HPGDPOLBCA2SMN1; SMN2HTR2A
SCHEMBL5713155 0.94 HTR2A (0.59) CA2HTR2ACA1CA12CA9
SCHEMBL6820400 0.92 HTR2A (0.62) CA2HTR2ACA1CA12CA9
SCHEMBL27030686 0.92 HTR2A (0.62) CA2HTR2ACA1CA12CA9
SCHEMBL11675017 0.92 HTR2A (0.62) CA2HTR2ACA1CA12CA9
Hydrochloric Acid SCHEMBL9615128 0.90 HTR2A (0.60) CA2HTR2ACA1CA12CA9
Phosphoric Acid SCHEMBL28200804 0.89 ENPP2 (0.51) HPGDPOLBCA2SMN1; SMN2CA1
Oxalic Acid SCHEMBL28200805 0.89 HPGD (0.56) HPGDPOLBCA2SMN1; SMN2CA1
Sulfuric Acid SCHEMBL28200211 0.89 CA2 (0.56) HPGDPOLBCA2SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918052-B1 Improved polymeric mdi color BAYER AG (US) 2003-05-28 EP claimed
WO-2022040157-A1 BORON CONTAINING COMPOUNDS AND THEIR USES 5METIS, INC. (US) 2022-02-24 WO disclosed
WO-2022040157-A1 BORON CONTAINING COMPOUNDS AND THEIR USES 5METIS, INC. (US) 2022-02-24 WO disclosed
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 US disclosed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 US disclosed
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
US-9732109-B2 Pesticidal compositions DOW AGROSCIENCES LLC (US) 2017-08-15 US disclosed
EP-2247603-B1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2016-09-28 EP disclosed
EP-2461688-B1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2016-03-16 EP disclosed
US-9179681-B2 Pesticidal compositions DOW AGROSCIENCES LLC (US) 2015-11-10 US disclosed
EP-2024419-A2 CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES University of Washington (US) 2009-02-18 EP disclosed
WO-2007133633-A2 CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES UNIVERSITY OF WASHINGTON (US) 2007-11-22 WO disclosed
EP-0977743-A1 PROTEASE INHIBITORS Smithkline Beecham (US) 2000-02-09 EP disclosed
WO-1998049152-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-05 WO disclosed
EP-0596983-B1 MONO- AND DIFLUOROACETYLPHENYL HYDRAZINE COMPOUNDS AS SILVER HALIDE ADJUVANTS DU PONT (US) 1995-11-02 EP disclosed
EP-0596983-A1 MONO- AND DIFLUOROACETYLPHENYL HYDRAZINE COMPOUNDS AS SILVER HALIDE ADJUVANTS. DU PONT (US) 1994-05-18 EP disclosed
US-5252426-A Lithogrpahic film coated with silver halide emulsions can produce high contrast images E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-10-12 US disclosed
WO-1993003414-A1 MONO- AND DIFLUOROACETYLPHENYL HYDRAZINE COMPOUNDS AS SILVER HALIDE ADJUVANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-18 WO disclosed
US-3979412-A Process for producing 3-anilino-5-pyrazolones FUJI PHOTO FILM CO., LTD. (JA) 1976-09-07 US disclosed
US-3933874-A Method for preparing of β-anilino-β-hydrazinoacrylates FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts HPD, TYR, PDK2 HPGD 390/4885POLB 892/4885CA2 931/4885
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts HPD, TYR, PDK2 HPGD 390/4885POLB 892/4885CA2 931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.