SCHEMBL12299587

SCHEMBL12299587

CC(=O)/C(=N/Nc1cccc(C(=O)O)c1)C(=O)Nc1ccc(NC(=O)/C(=N\Nc2cccc(C(=O)O)c2)C(C)=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.54
NPC1 O15118 10/20 0.54
RAB9A P51151 10/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
MAPK1 P28482 3/20 0.54
GAA P10253 5/20 0.54
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
KMT2A Q03164 7/20 0.51
MEN1 O00255 6/20 0.51
POLB P06746 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
GFER P55789 2/20 0.50
PAX8 Q06710 2/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.48
HPSE Q9Y251 1/20 0.48
RECQL P46063 1/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14524192 0.89 HIF1A (0.46) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL12299588 0.87 GFER (0.47) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL15216616 0.87 MAPT (0.55) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL12299595 0.85 MAPT (0.49) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL12299534 0.85 RAB9A (0.51) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL16552280 0.85 MAPT (0.59) MAPTNPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL12299581 0.84 GFER (0.52) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL18032016 0.84 PARP1 (0.48) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL12299488 0.83 RAB9A (0.64) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL12299515 0.83 NPC1 (0.48) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1790696-B1 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2013-04-10 EP disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed