SCHEMBL12299488

SCHEMBL12299488

COc1ccccc1NC(=O)/C(=N\Nc1cccc(C(=O)O)c1)C(C)=O

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 12/20 0.64
NPC1 O15118 10/20 0.64
MAPT P10636 7/20 0.58
ALDH1A1 P00352 3/20 0.58
MAPK1 P28482 2/20 0.58
SMN1; SMN2 Q16637 5/20 0.57
GAA P10253 4/20 0.57
KDM4E B2RXH2 1/20 0.57
KMT2A Q03164 7/20 0.53
MEN1 O00255 6/20 0.53
POLB P06746 2/20 0.50
CASP6 P55212 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.49
CDC25B P30305 1/20 0.48
MITF O75030 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
HPGD P15428 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12998571 0.88 ALDH1A1 (0.65) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299485 0.87 MAPT (0.56) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299491 0.86 ALDH1A1 (0.58) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299493 0.85 ALDH1A1 (0.63) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL13115109 0.85 ALDH1A1 (0.63) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299587 0.83 MAPT (0.54) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299489 0.80 ALDH1A1 (0.58) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299515 0.80 NPC1 (0.48) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL12299534 0.80 RAB9A (0.51) RAB9ANPC1MAPTALDH1A1MAPK1
SCHEMBL14435616 0.79 TDP1 (0.51) RAB9ANPC1MAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
WO-2007060263-A2 NON-AQUEOUS PIGMENT DISPERSIONS CONTAINING SPECIFIC DISPERSION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
WO-2007060264-A2 NON-AQUEOUS PIGMENT DISPERSIONS CONTAINING SPECIFIC DISPERION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
EP-1790697-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed
EP-1790696-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed