Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12301906 | 0.88 | PIK3CA (0.37) | MEN1KMT2APOLBRAB9AHTT | |
| SCHEMBL12302034 | 0.77 | MAPT (0.36) | MEN1KMT2APOLBRAB9AHTT | |
| SCHEMBL12301904 | 0.74 | APP (0.47) | ESR1HSD17B1HSD17B2ESR2APP | |
| SCHEMBL30924937 | 0.74 | ALDH1A1 (0.33) | MEN1KMT2APOLBRAB9AAPP | |
| SCHEMBL4822992 | 0.71 | MAPT (0.48) | POLBRAB9AHTTSNCANPC1 | |
| SCHEMBL30924931 | 0.70 | LDHA (0.45) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL6658511 | 0.69 | KDM4E (0.42) | MEN1KMT2APOLBRAB9AHTT | |
| SCHEMBL17967724 | 0.66 | MAPT (0.43) | POLBRAB9AHTTNPC1 | |
| SCHEMBL14982704 | 0.66 | MAPT (0.45) | MEN1KMT2APOLBRAB9AAPP | |
| SCHEMBL16418446 | 0.66 | SNCA (0.39) | MEN1KMT2APOLBRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885718-B1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | LIFE TECHNOLOGIES CORP (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9366676-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | MOLECULAR PROBES, INC. | 2015-11-05 | — | — | US | disclosed |
| US-9115397-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150004597-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | LIFE TECHNOLOGIES CORP (US) | 2015-01-01 | — | — | US | disclosed |
| US-8865904-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |
| US-8865904-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130224735-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130224735-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2013-08-29 | — | — | US | disclosed |
| US-20120288855-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
| US-20110217699-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2011-09-08 | — | — | US | disclosed |
| US-7943777-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100143917-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | Life Technologies Corporation (US) | 2010-06-10 | — | — | US | disclosed |
| US-7598390-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2009-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110217699-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | ESR1 2908/4885MEN1 3097/4885KMT2A 1014/4885 |
| US-20120288855-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | ESR1 2908/4885MEN1 3097/4885KMT2A 1014/4885 |
| US-20100143917-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | POLRMT, DNA2, NSUN2 | ESR1 2908/4885MEN1 3097/4885KMT2A 1014/4885 |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | ESR1 2908/4885MEN1 3097/4885KMT2A 1014/4885 |
| US-20150004597-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | ESR1 2908/4885MEN1 3097/4885KMT2A 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.