Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 2/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12301993 | 0.86 | ADRA1D (0.32) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL12301969 | 0.86 | HTR7 (0.32) | ERN1HTR7 | |
| SCHEMBL12301982 | 0.85 | KDM4E (0.31) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL12302037 | 0.85 | KDM4E (0.47) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL12301934 | 0.84 | ERN1 (0.32) | NPC1ALDH1A1POLBMAPTHTT | |
| SCHEMBL12301976 | 0.84 | — | — | |
| SCHEMBL15219003 | 0.83 | BACE1 (0.32) | — | |
| SCHEMBL12301954 | 0.83 | — | — | |
| SCHEMBL12301983 | 0.83 | PTGER2 (0.30) | — | |
| SCHEMBL12301965 | 0.82 | HTR7 (0.35) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885718-B1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | LIFE TECHNOLOGIES CORP (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9366676-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | MOLECULAR PROBES, INC. | 2015-11-05 | — | — | US | disclosed |
| US-9115397-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150004597-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | LIFE TECHNOLOGIES CORP (US) | 2015-01-01 | — | — | US | disclosed |
| US-8865904-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130224735-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2013-08-29 | — | — | US | disclosed |
| US-20120288855-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
| US-20110217699-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2011-09-08 | — | — | US | disclosed |
| US-7943777-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100143917-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | Life Technologies Corporation (US) | 2010-06-10 | — | — | US | disclosed |
| US-7598390-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2009-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110217699-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | KDM4E 2506/4885MEN1 3097/4885NPC1 2240/4885 |
| US-20120288855-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | KDM4E 2506/4885MEN1 3097/4885NPC1 2240/4885 |
| US-20100143917-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | POLRMT, DNA2, NSUN2 | KDM4E 2506/4885MEN1 3097/4885NPC1 2240/4885 |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | KDM4E 2506/4885MEN1 3097/4885NPC1 2240/4885 |
| US-20150004597-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | KDM4E 2506/4885MEN1 3097/4885NPC1 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.