SCHEMBL12304032

SCHEMBL12304032

CS(=O)(=O)c1cc2c(c(O)c1O)C(=O)c1ccccc1C2=O

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGAM1 P18669 8/20 0.73
PKLR P30613 12/20 0.71
PTPN1 P18031 2/20 0.71
BCL2 P10415 1/20 0.62
MCL1 Q07820 1/20 0.62
ELANE P08246 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alizarin Red SCHEMBL29372853 0.85 PGAM1 (1.00) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL1203855 0.85 PGAM1 (1.00) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL29630358 0.85 PGAM1 (1.00) PGAM1PKLRPTPN1BCL2MCL1
SCHEMBL1506814 0.83 PGAM1 (0.73) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL433811 0.83 PGAM1 (0.97) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL728495 0.83 PGAM1 (0.97) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL27607379 0.83 PGAM1 (0.97) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL728494 0.82 PKLR (1.00) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL29368828 0.82 PKLR (1.00) PGAM1PKLRPTPN1BCL2MCL1
Alizarin Red SCHEMBL29349481 0.82 PKLR (1.00) PGAM1PKLRPTPN1BCL2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895725-B2 Use of 9, 10-anthraquinone compounds SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2014-11-25 US disclosed
US-20110224414-A1 USE OF 9, 10-ANTHRAQUINONE COMPOUNDS SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224414-A1 USE OF 9, 10-ANTHRAQUINONE COMPOUNDS HCCS, CYC1, C1S PGAM1 4080/4885PKLR 3805/4885PTPN1 1835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.