Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alizarin Red. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 13/20 | 1.00 |
| ▸ | PGAM1 | P18669 | 7/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | BCL2 | P10415 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alizarin Red SCHEMBL29368828 | 1.00 | PKLR (1.00) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL29349481 | 1.00 | PKLR (1.00) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL29534709 | 0.98 | PKLR (0.97) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL1203855 | 0.83 | PGAM1 (1.00) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL29630358 | 0.83 | PGAM1 (1.00) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL29372853 | 0.83 | PGAM1 (1.00) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL433811 | 0.82 | PGAM1 (0.97) | PKLRPGAM1PTPN1BCL2MCL1 | |
| SCHEMBL1506814 | 0.82 | PGAM1 (0.73) | PKLRPGAM1PTPN1BCL2MCL1 | |
| SCHEMBL12304032 | 0.82 | PGAM1 (0.73) | PKLRPGAM1PTPN1BCL2MCL1 | |
| Alizarin Red SCHEMBL728495 | 0.82 | PGAM1 (0.97) | PKLRPGAM1PTPN1BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117996232-A | Additive for aqueous zinc ion battery electrolyte and application thereof | 黑龙江大学 | 2024-05-07 | — | — | CN | claimed |
| CN-116199247-A | Preparation method of boron-containing aluminum sol for coating ternary positive electrode material of lithium battery | 福州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-115433338-A | Preparation method of water-soluble ultraviolet-curing matte hyperbranched polyurethane acrylic resin | 武汉超支化树脂科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| EP-3906338-A1 | WRITING AND/OR DRAWING SYSTEM COMPRISING PH SENSITIVE DYE AND METHOD THEREOF | Sanko Tekstil Isletmeleri San. Ve Tic. A.S. (TR) | 2021-11-10 | — | — | EP | claimed |
| CN-113544327-A | Writing and/or painting system comprising a pH sensitive dye and method thereof | 尚科纺织企业工业及贸易公司 | 2021-10-22 | — | — | CN | claimed |
| CN-109107546-B | Synthetic method and application of alizarin red-S chelating resin | 河南省岩石矿物测试中心 | 2021-06-04 | — | — | CN | claimed |
| WO-2020141216-A1 | WRITING AND/OR DRAWING SYSTEM COMPRISING PH SENSITIVE DYE AND METHOD THEREOF | SANKO TEKSTIL ISLETMELERI SAN. VE TIC. A.S. (TR) | 2020-07-09 | — | — | WO | claimed |
| CN-111097541-A | Dye-sensitized black titanium dioxide and preparation method and application thereof | 中国科学院上海硅酸盐研究所 | 2020-05-05 | — | — | CN | claimed |
| CN-109107546-A | Synthetic method and application of alizarin red-S chelate forming resin | 河南省岩石矿物测试中心 | 2019-01-01 | — | — | CN | claimed |
| CN-106576963-A | Management method for promoting prematurity of potted butterfly orchid | 安徽裕龙种植农民专业合作社 | 2017-04-26 | — | — | CN | claimed |
| CN-1332642-C | Composition for self-diagnosis and reduction catalyst treatment of permanent and hair straightener and method of preparation | BEEBONG FINE CO LTD (KR) | 2007-08-22 | — | — | CN | claimed |
| CN-1879711-A | A Chinese medicinal composition for treating gastric disease, its preparation process and quality control method | GAO QINGCHUAN (CN) | 2006-12-20 | — | — | CN | claimed |
| CN-1285370-C | Pharmaceutical composition for treating gastritis, gastric ulcer and doudenal ulcer | QINGDAO GROWFUL PHARMACEUTICAL (CN) | 2006-11-22 | — | — | CN | claimed |
| CN-1758894-A | Composition for self-diagnosis and reduction catalyst treatment of permanent and hair straightener and method of preparation | BEEBONG FINE CO LTD (KR) | 2006-04-12 | — | — | CN | claimed |
| CN-1730025-A | Pharmaceutical composition for treating gastritis, gastric ulcer and doudenal ulcer | QINGDAO GROWFUL PHARMACEUTICAL (CN) | 2006-02-08 | — | — | CN | claimed |
| EP-0454058-B1 | Use of anthraquinone derivatives in the prophylaxis and treatment of viral diseases | LOHMANN RUDOLF LOMAPHARM (DE) | 1998-06-17 | — | — | EP | claimed |
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | claimed |
| US-5250385-A | Photosensitivity, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-05 | — | — | US | claimed |
| EP-0454058-A2 | Use of anthraquinone derivatives in the prophylaxis and treatment of viral diseases | LOMAPHARM Rudolf Lohmann GmbH KG Pharmazeutische Fabrik (DE) | 1991-10-30 | — | — | EP | claimed |
| US-4522963-A | Procedure for curing unsaturated polyester resins | MUANYAGIPARI KUTATO INTEZET (HU) | 1985-06-11 | — | — | US | claimed |