SCHEMBL12306232

SCHEMBL12306232

CCn1c2ccccc2c2cc(/C=C/c3ccc(-c4ccc(/C=C/c5ccc6c(c5)c5ccccc5n6C)cc4)cc3)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
HTT P42858 3/20 0.58
POLB P06746 1/20 0.58
PKM P14618 1/20 0.58
SRC P12931 4/20 0.55
BCHE P06276 3/20 0.55
ACHE P22303 3/20 0.55
MAPT P10636 6/20 0.52
ALDH1A1 P00352 5/20 0.52
HPGD P15428 5/20 0.52
LMNA P02545 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
HSD17B10 Q99714 2/20 0.52
USP2 O75604 1/20 0.52
TSHR P16473 1/20 0.52
CASP1 P29466 1/20 0.52
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
MAPK1 P28482 1/20 0.51
HBB P68871 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18473305 1.00 KDM4E (0.58) KDM4EHTTPOLBPKMSRC
SCHEMBL11977563 0.96 KDM4E (0.54) KDM4EHTTPOLBPKMSRC
SCHEMBL31281511 0.94 KDM4E (0.63) KDM4EHTTPOLBPKMSRC
SCHEMBL29449353 0.94 KDM4E (0.63) KDM4EHTTPOLBPKMSRC
SCHEMBL85678 0.94 KDM4E (0.63) KDM4EHTTPOLBPKMSRC
SCHEMBL385469 0.94 KDM4E (0.63) KDM4EHTTPOLBPKMSRC
SCHEMBL29389834 0.94 KDM4E (0.63) KDM4EHTTPOLBPKMSRC
SCHEMBL13013216 0.90 KDM4E (0.59) KDM4EHTTPOLBPKMSRC
SCHEMBL3443606 0.90 KDM4E (0.68) KDM4EHTTPOLBPKMSRC
SCHEMBL29415213 0.90 KDM4E (0.68) KDM4EHTTPOLBPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923148-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2018-03-20 US disclosed
US-20170194568-A9 Electroluminescent Device UDC IRELAND LIMITED (IE) 2017-07-06 US disclosed
US-20130079517-A1 Electroluminescent Device BASF SE (DE) 2013-03-28 US disclosed
US-8012602-B2 Blue emitting, durable, organoelectroluminescent layers containing pyrimidine moieties; full color displays; light emission efficiency and brightness BASF SE (DE) 2011-09-06 US disclosed
US-20100240892-A1 ELECTROLUMINESCENT DEVICE SCHAEFER THOMAS 2010-09-23 US disclosed
US-20090102373-A1 Electroluminescent device HAYOZ PASCAL 2009-04-23 US disclosed
US-20080199726-A1 Electroluminescent Device CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2008-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090102373-A1 Electroluminescent device TAAR5, TYR, TRPC5 KDM4E 1609/4885HTT 1701/4885POLB 3916/4885
US-20170194568-A9 Electroluminescent Device DPYD, PNPO, TYMP KDM4E 1418/4885HTT 3675/4885POLB 796/4885
US-20080199726-A1 Electroluminescent Device TPMT, THPO, KYNU KDM4E 1166/4885HTT 3087/4885POLB 2958/4885
US-20130079517-A1 Electroluminescent Device DPYD, PNPO, TYMP KDM4E 1418/4885HTT 3675/4885POLB 796/4885
US-20100240892-A1 ELECTROLUMINESCENT DEVICE PNPO, ODC1, AXL KDM4E 1312/4885HTT 3444/4885POLB 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.