Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306588 | 0.92 | KDM4E (0.44) | KDM4EATML3MBTL1PDK2HDAC4 | |
| SCHEMBL12306519 | 0.92 | KDM4E (0.44) | KDM4EATML3MBTL1PDK2HDAC4 | |
| SCHEMBL13443638 | 0.92 | TUBB4A (0.33) | KDM4EATML3MBTL1TUBB4ATUBB | |
| SCHEMBL13444192 | 0.92 | TUBB4A (0.33) | KDM4EATML3MBTL1TUBB4ATUBB | |
| SCHEMBL13443664 | 0.92 | TUBB4A (0.35) | KDM4EATML3MBTL1TUBB4ATUBB | |
| SCHEMBL13432995 | 0.91 | TUBB4A (0.34) | KDM4EATML3MBTL1TUBB4ATUBB | |
| SCHEMBL20232325 | 0.91 | KDM4E (0.43) | KDM4EATML3MBTL1PDK2HDAC4 | |
| SCHEMBL13443670 | 0.90 | TUBB4A (0.34) | KDM4EATML3MBTL1TUBB4ATUBB | |
| SCHEMBL19271573 | 0.90 | TUBB4A (0.34) | KDM4EATML3MBTL1TUBB4ATUBB | |
| SCHEMBL13444239 | 0.90 | TUBB4A (0.34) | KDM4EATML3MBTL1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013160-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8013160-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-7781628-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781628-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7683225-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-7683225-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20080303433-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
| US-20080303433-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | LEF1, FLNA, AFF2 | KDM4E 1471/4885ATM 2869/4885L3MBTL1 816/4885 |
| US-20080303433-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | FLNA, AFF2, LEF1 | KDM4E 1466/4885ATM 2691/4885L3MBTL1 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.