Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16314010 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53ALDH1A1CCR5POLB | |
| SCHEMBL12254884 | 0.81 | NPSR1 (0.42) | MEN1KMT2ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL21985484 | 0.78 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL27413462 | 0.77 | CYP2C19 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL23344403 | 0.76 | GAA (0.41) | SMN1; SMN2TP53ALDH1A1CCR5HSD17B10 | |
| SCHEMBL20407539 | 0.76 | CCR5 (0.33) | SMN1; SMN2TP53CCR5HSD17B10 | |
| SCHEMBL1285155 | 0.76 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL21227418 | 0.74 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL23709496 | 0.74 | TP53 (0.49) | MEN1KMT2ASMN1; SMN2TP53MTNR1A | |
| SCHEMBL16313927 | 0.73 | CCR5 (0.30) | MEN1KMT2ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022113-B2 | Composition containing aziridino groups and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-09-20 | — | — | US | disclosed |
| EP-1984427-B1 | COMPOSITION CONTAINING AZIRIDINO GROUPS AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2009-10-28 | — | — | EP | disclosed |