Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12307258 | 0.84 | MEN1 (0.47) | SMN1; SMN2TP53ALDH1A1CCR5NAMPT | |
| SCHEMBL12254884 | 0.79 | NPSR1 (0.42) | SMN1; SMN2TP53ALDH1A1CCR5MAPT | |
| SCHEMBL23344403 | 0.79 | GAA (0.41) | SMN1; SMN2TP53ALDH1A1ANPEPDNPEP | |
| SCHEMBL7944266 | 0.77 | ANPEP (0.52) | SMN1; SMN2ALDH1A1ANPEPDNPEPNAMPT | |
| SCHEMBL21985484 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53ALDH1A1ANPEPDNPEP | |
| SCHEMBL20407539 | 0.75 | CCR5 (0.33) | SMN1; SMN2TP53ANPEPDNPEPCCR5 | |
| SCHEMBL27413462 | 0.72 | CYP2C19 (0.43) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16313927 | 0.72 | CCR5 (0.30) | CCR5 | |
| SCHEMBL26857860 | 0.72 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1ANPEPDNPEPHPGD | |
| SCHEMBL7947948 | 0.69 | KMT2A (0.41) | SMN1; SMN2TP53ALDH1A1ANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022113-B2 | Composition containing aziridino groups and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-09-20 | — | — | US | disclosed |
| EP-1984427-B1 | COMPOSITION CONTAINING AZIRIDINO GROUPS AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2009-10-28 | — | — | EP | disclosed |