Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137892 | 0.99 | PTGS1 (0.48) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL14865806 | 0.92 | PTGS1 (0.44) | PTGS1ADORA1 | |
| SCHEMBL14865834 | 0.91 | PTGS1 (0.41) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL9915839 | 0.90 | PTGS1 (0.41) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL13401328 | 0.88 | PTGS1 (0.43) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL14865832 | 0.88 | PTGS1 (0.47) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL12265730 | 0.88 | PTGS1 (0.47) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL13977982 | 0.87 | PTGS1 (0.45) | PTGS1ADORA1KDM4EMEN1USP2 | |
| SCHEMBL12265260 | 0.87 | PTGS1 (0.41) | PTGS1ADORA1KMT2A | |
| Hydrochloric Acid SCHEMBL29349584 | 0.87 | PTGS1 (0.42) | PTGS1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322107-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | CAYMAN CHEMICAL COMPANY, INCORPORATED | 2015-11-12 | — | — | US | disclosed |
| US-20150323542-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2015-11-12 | — | — | US | disclosed |
| US-9120820-B2 | Fluorescent molecular probes for use in assays that measure test compound competitive binding with SAM-utilizing proteins | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2015-09-01 | — | — | US | disclosed |
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-22 | — | — | US | disclosed |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322107-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | PTGS1 4718/4885ADORA1 1863/4885KDM4E 4555/4885 |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | DCLRE1B, NSUN2, MTX2 | PTGS1 4024/4885ADORA1 1026/4885KDM4E 3742/4885 |
| US-20150323542-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | PTGS1 4718/4885ADORA1 1863/4885KDM4E 4555/4885 |
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | PTGS1 4718/4885ADORA1 1863/4885KDM4E 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.