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Sugi Predict / Compounds / Ethyl Acetate

Ethyl Acetate

Ethyl Acetate

SCHEMBL1231

CCN(CC)CC.CCOC(C)=O.ClCCl

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.64
▸ LMNA P02545 1/20 0.64
▸ HSD17B10 Q99714 1/20 0.64
▸ TSHR P16473 1/20 0.41
▸ TRPA1 O75762 1/20 0.39
▸ GAA P10253 2/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ MGAM O43451 1/20 0.37
▸ SI P14410 1/20 0.37
▸ MGAM2 Q2M2H8 1/20 0.37
▸ SOAT1 P35610 1/20 0.37
▸ CA12 O43570 2/20 0.35
▸ CA1 P00915 2/20 0.35
▸ CA2 P00918 2/20 0.35
▸ CA9 Q16790 2/20 0.35
▸ APOBEC3A P31941 1/20 0.35
▸ APOBEC3G Q9HC16 1/20 0.35
▸ GLO1 Q04760 1/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL1893047 0.98 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL5861342 0.93 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL276158 0.93 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL6046507 0.93 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL6347449 0.93 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL3507062 0.91 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL11579143 0.91 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL6252701 0.91 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL882 0.91 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRTRPA1
Ethyl Acetate SCHEMBL2385899 0.89 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499528-B Terbutaline sulfate intermediate, preparation method thereof and method for preparing terbutaline sulfate by using terbutaline sulfate intermediate 成都瑞特恩科技有限公司 2023-06-20 — — CN disclosed
CN-114075205-A CDK kinase inhibitor, preparation method, pharmaceutical composition and application thereof 隆泰申医药科技(南京)有限公司 2022-02-22 — — CN disclosed
CN-111499528-A Terbutaline sulfate intermediate, preparation method thereof and method for preparing terbutaline sulfate by using terbutaline sulfate intermediate 成都瑞特恩科技有限公司 2020-08-07 — — CN disclosed
US-9983218-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2018-05-29 — — US disclosed
US-20180024144-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF ABBVIE INC. (US) 2018-01-25 — — US disclosed
US-9625475-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2017-04-18 — — US disclosed
US-9285319-B2 Nucleic acid base analogs with quenching and fluorescent activities and applications thereof RIKEN (JP) 2016-03-15 — — US disclosed
US-9212167-B2 Mitochondrial targeted stimulators of apoptosis THE ROCKEFELLER UNIVERSITY (US) 2015-12-15 — — US disclosed
US-20150353550-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF ABBVIE INC (US) 2015-12-10 — — US disclosed
US-9063126-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2015-06-23 — — US disclosed
EP-0640072-A1 SUBSTITUTED PYRIDINES, THEIR PREPARATION AND PHARMACEUTICAL USE BTG INTERNATIONAL LIMITED (GB) 1995-03-01 — — EP disclosed
US-5360800-A Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives GLAXO GROUP LIMITED (GB) 1994-11-01 — — US disclosed
EP-0306323-B1 Lactam derivatives GLAXO GROUP LTD (GB) 1994-09-21 — — EP disclosed
EP-0594629-A1 HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL USE BRITISH TECHNOLOGY GROUP LTD (GB) 1994-05-04 — — EP disclosed
WO-1994004550-A1 CHOLESTERYL-MODIFIED TRIPLE-HELIX FORMING OLIGONUCLEOTIDES AND USES THEREOF TRIPLEX PHARMACEUTICAL CORPORATION (US) 1994-03-03 — — WO disclosed
WO-1993023375-A1 SUBSTITUTED PYRIDINES, THEIR PREPARATION AND PHARMACEUTICAL USE BRITISH TECHNOLOGY GROUP LIMITED (GB) 1993-11-25 — — WO disclosed
US-5208235-A Phosphonic or phosphinic acid derivatives as inhibitors of angiotnesin II for cardiovascular disorders and hypotensives E. R. SQUIBB & SONS, INC. (US) 1993-05-04 — — US disclosed
WO-1992016507-A1 HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL USE BRITISH TECHNOLOGY GROUP LIMITED (GB) 1992-10-01 — — WO disclosed
US-4943566-A ANTAGONISTIC TOWARD GLUCOCORTICOIDS AND PROGESTERONE ROUSSEL UCLAFI 1990-07-24 — — US disclosed
EP-0306323-A2 Lactam derivatives GLAXO GROUP LIMITED (GB) 1989-03-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180024144-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF IDO1, IDO2, TPH1 ALDH1A1 1307/4885LMNA 1983/4885HSD17B10 1405/4885
US-20150353550-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF IDO1, IDO2, TPH1 ALDH1A1 1307/4885LMNA 1983/4885HSD17B10 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.