SCHEMBL1231017

SCHEMBL1231017

CCc1cccc(CC)c1C(N)N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.48
GABRB2 P47870 5/20 0.48
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SLC6A2 P23975 2/20 0.34
TAAR1 Q96RJ0 2/20 0.34
MAOA P21397 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MGLL Q99685 1/20 0.34
PDK2 Q15119 1/20 0.34
ELANE P08246 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5167903 0.79 GABRA1 (0.43) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL9734348 0.77 GABRA1 (0.50) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL10334968 0.77 GABRA1 (0.56) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL10334969 0.75 LMNA (0.59) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL18243183 0.75 GABRA1 (0.54) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL21730322 0.74 GABRA1 (0.39) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL815600 0.74 GABRA1 (0.39) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL23735841 0.73 GABRA1 (0.46) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL18242436 0.73 GABRA1 (0.52) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1
SCHEMBL18843526 0.73 GABRA1 (0.52) GABRA1GABRB2LMNASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119871969-A Self-repairing new energy tire and production method thereof 山东昌丰轮胎有限公司 2025-04-25 CN claimed
WO-2020138661-A1 POLYURETHANE WATERPROOF FLOORING PAINT CONTAINING CHAIN EXTENDER COMPOSITION 지혜경 2020-07-02 WO claimed
WO-2020138660-A1 CHAIN EXTENDER COMPOSITION FOR POLYURETHANE 지혜경 2020-07-02 WO claimed
US-20130112108-A1 PRODUCING METHOD OF INK COMPOSITION FOR FORMING ABSORPTION LAYER OF THIN FILM CELLS BOSIN TECHNOLOGY CO., LTD. (TW) 2013-05-09 US claimed
US-20110023750-A1 INK COMPOSITION FOR FORMING ABSORBERS OF THIN FILM CELLS AND PRODUCING METHOD THEREOF Wang, Kuan-Che (TW) 2011-02-03 US claimed
JP-8118508-A None JP disclosed
JP-4288042-A None JP disclosed
US-20250270363-A1 POLYURETHANE RESIN, ELASTIC MOLDED ARTICLE, AND METHOD FOR PRODUCING POLYURETHANE RESIN MITSUI CHEMICALS, INC. (JP) 2025-08-28 US disclosed
CN-119871969-A Self-repairing new energy tire and production method thereof 山东昌丰轮胎有限公司 2025-04-25 CN disclosed
EP-4512841-A1 POLYURETHANE RESIN, ELASTIC MOLDED ARTICLE, AND METHOD FOR PRODUCING POLYURETHANE RESIN Mitsui Chemicals, Inc. (JP) 2025-02-26 EP disclosed
CN-118900865-A Polyurethane resin, elastic molded article, and method for producing polyurethane resin 三井化学株式会社 2024-11-05 CN disclosed
WO-2023204126-A1 POLYURETHANE RESIN, ELASTIC MOLDED ARTICLE, AND METHOD FOR PRODUCING POLYURETHANE RESIN 三井化学株式会社 2023-10-26 WO disclosed
EP-0482499-A2 Process for alkylation of aromatic diamines and catalyst for said process ALBEMARLE CORPORATION (US) 1992-04-29 EP disclosed
US-5106874-A From polyisocyanate and polyoxypropylene glycol THE DOW CHEMICAL COMPANY (US) 1992-04-21 US disclosed
EP-0255930-B1 POLYURETHANE FOAMS INCORPORATING ALKOXYLATED AROMATIC DIAMINE AND ACETYLENIC GLYCOL AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-12-11 EP disclosed
EP-0408201-A1 Process for preparing elastomeric polyurethane or polyurethane-urea polymers, and polyurethanes so prepared THE DOW CHEMICAL COMPANY (US) 1991-01-16 EP disclosed
WO-1990015835-A1 PROCESS FOR PREPARING ELASTOMERIC POLYURETHANE OR POLYURETHANE-UREA POLYMERS, AND POLYURETHANES SO PREPARED THE DOW CHEMICAL COMPANY (US) 1990-12-27 WO disclosed
US-4950789-A USEFUL FOR MAKING REACTION INJECTION MOLDED POLYURETHANES, POLYUREAS THE DOW CHEMICAL COMPANY (US) 1990-08-21 US disclosed
US-4743628-A CROSSLINKING, HIGHER LOAD-BEARING, TEAR STRENGTH, ELONGATION AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-05-10 US disclosed
EP-0255930-A2 Polyurethane foams incorporating alkoxylated aromatic diamine and acetylenic glycol AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-02-17 EP disclosed