Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20713445 | 0.89 | GABRA1 (0.41) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL3088973 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL12446949 | 0.84 | GABRA1 (0.41) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL21736785 | 0.84 | GABRA1 (0.52) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9336892 | 0.84 | GABRA1 (0.52) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL15371487 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6546378 | 0.84 | L3MBTL1 (0.46) | L3MBTL1DAO | |
| SCHEMBL18243183 | 0.82 | GABRA1 (0.54) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11883134 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10701444 | 0.81 | KDM4E (0.47) | L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683294-B2 | 5-5 fused rings as C5a inhibitors | CHEMOCENTRYX, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| CN-1018908-B | COLOR-DEVELOPING SHEETS USING IN PRESSURE-SENSING CARBON PAPER | MITSUI TOATSU CHEMICALS (JP) | 1992-11-04 | — | — | CN | disclosed |
| EP-0233450-B1 | LINEAR SALICYLIC ACID COPOLYMERS AND THEIR METAL SALTS, PRODUCTION PROCESS THEREOF, COLOR-DEVELOPING AGENTS COMPRISING METAL-RESINS OF THE COPOLYMERS, AND COLOR-DEVELOPING SHEETS EMPLOYING THE AGENTS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |
| CN-1007814-B | Linear salicylic acid copolymer and method for producing metal salt thereof, and color-developing agent containing copolymer metal salt, and color-developing paper using the same | MITSUI TOATSU CHEMICALS (JP) | 1990-05-02 | — | — | CN | disclosed |
| CN-1040543-A | Linear salicylic acid copolymer, process for producing metal salt thereof, color-developing agent containing copolymer metal salt, and color-developing paper using the same | MITSUI TOATSU CHEMICALS (JP) | 1990-03-21 | — | — | CN | disclosed |
| US-4783521-A | Linear salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal-resins of the copolymers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-11-08 | — | — | US | disclosed |
| CN-87100709-A | Linear salicylic acid copolymer and method for producing metal salt thereof, and color-developing agent containing copolymer metal salt, and color-developing paper using the same | — | 1987-09-02 | — | — | CN | disclosed |
| EP-0233450-A2 | Linear salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal-resins of the copolymers, and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683294-B2 | 5-5 fused rings as C5a inhibitors | C5AR1, C5AR2, C3AR1 | GABRA1 1492/4885GABRB2 2152/4885LMNA 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.