Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrogallol SCHEMBL28231306 | 0.82 | ERN1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL11758757 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14201283 | 0.77 | — | — | |
| SCHEMBL8572251 | 0.75 | — | — | |
| SCHEMBL6451600 | 0.70 | — | — | |
| SCHEMBL2799435 | 0.70 | TDP1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL21608 | 0.70 | LMNA (0.40) | ALDH1A1TDP1 | |
| SCHEMBL11124454 | 0.70 | — | — | |
| SCHEMBL14855811 | 0.69 | — | — | |
| SCHEMBL8942761 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230476-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230476-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | PIK3CA, PIK3CB, PIK3C2B | ALDH1A1 4394/4885TDP1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.