Pyrogallol

Pyrogallol

SCHEMBL28231306

C=C(C)C(=O)N(C=O)CC.Oc1cccc(O)c1O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.40
IAPP P10997 8/20 0.38
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
LMNA P02545 2/20 0.36
ADAMTS4 O75173 1/20 0.36
ALDH1A1 P00352 1/20 0.36
EGFR P00533 1/20 0.36
FYN P06241 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
MMP8 P22894 1/20 0.36
CA6 P23280 1/20 0.36
CDK2 P24941 1/20 0.36
MMP12 P39900 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12313622 0.82 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL28435736 0.74 NPC1 (0.43) LMNAALDH1A1TDP1CA12CA9
Pyrogallol SCHEMBL4947548 0.70 ALDH1A1 (0.55) ERN1IAPPCA1CA2LMNA
Pyrogallol SCHEMBL10407842 0.70 ALDH1A1 (0.55) ERN1IAPPCA1CA2LMNA
SCHEMBL27976696 0.69 IAPP (0.37) IAPPCA1CA2ALDH1A1THRB
Pyrogallol SCHEMBL10717987 0.68 ALDH1A1 (0.57) ERN1IAPPCA1CA2LMNA
Pyrogallol SCHEMBL2266603 0.68 ALDH1A1 (0.71) ERN1IAPPCA1CA2LMNA
Pyrogallol SCHEMBL225781 0.68 CA1 (0.71) ERN1IAPPCA1CA2LMNA
Pyrogallol SCHEMBL16341956 0.66 ALDH1A1 (0.60) IAPPCA1CA2LMNAADAMTS4
SCHEMBL10809 0.66 THRB (0.36) IAPPCA1CA2ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108294957-A The gear division resin adhesive of the amide derivatives of polyphenol containing unsaturated fatty acid 成都交大麦迪克科技有限公司 2018-07-20 CN disclosed