Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 12/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ODC1 | P11926 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666102 | 0.90 | HIF1A (0.39) | COXFA4HIF1AEPAS1PTGS1PTGS2 | |
| SCHEMBL12315598 | 0.88 | COXFA4 (0.52) | COXFA4HIF1AEPAS1ODC1HSP90AA1 | |
| SCHEMBL13535471 | 0.81 | COXFA4 (0.58) | COXFA4HIF1AEPAS1ODC1HSP90AA1 | |
| SCHEMBL12315606 | 0.79 | COXFA4 (0.52) | COXFA4HIF1AHSP90AA1LMNAHTT | |
| SCHEMBL14098883 | 0.77 | HIF1A (0.51) | COXFA4HIF1AEPAS1HSP90AA1EP300 | |
| SCHEMBL12315464 | 0.75 | PTGS1 (0.39) | HIF1AEPAS1PTGS1PTGS2XDH | |
| SCHEMBL12315596 | 0.70 | COXFA4 (0.43) | COXFA4HIF1AEPAS1ODC1HSP90AA1 | |
| SCHEMBL14666129 | 0.68 | COXFA4 (0.48) | COXFA4HIF1AEPAS1PTGS1PTGS2 | |
| SCHEMBL9475096 | 0.68 | HIF1A (0.52) | COXFA4HIF1AEPAS1EP300 | |
| SCHEMBL12315461 | 0.65 | COXFA4 (0.62) | COXFA4HIF1AEPAS1ODC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263042-B2 | Contrast agents for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-09-11 | — | — | US | disclosed |