SCHEMBL123158

SCHEMBL123158

C=C(CCCCC)C(=C)C(=C)C(=C)C(=C)C(=C)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.43
CES1 P23141 4/20 0.43
FAAH O00519 3/20 0.42
AKR1B1 P15121 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
SOAT1 P35610 1/20 0.41
GPR84 Q9NQS5 7/20 0.40
PPARG P37231 6/20 0.40
PPARD Q03181 6/20 0.40
PPARA Q07869 6/20 0.40
HDAC11 Q96DB2 5/20 0.40
TSHR P16473 4/20 0.40
ALDH1A1 P00352 2/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029026 0.98 CES2 (0.45) CES2CES1FAAHMEN1KMT2A
SCHEMBL5027330 0.98 CES2 (0.45) CES2CES1FAAHMEN1KMT2A
SCHEMBL3984615 0.98 CES2 (0.45) CES2CES1FAAHMEN1KMT2A
SCHEMBL27727796 0.98 CES2 (0.45) CES2CES1FAAHMEN1KMT2A
SCHEMBL1407233 0.98 CES2 (0.45) CES2CES1FAAHMEN1KMT2A
SCHEMBL5038259 0.96 CES2 (0.46) CES2CES1FAAHMEN1KMT2A
SCHEMBL3738395 0.94 CES1 (0.41) CES2CES1FAAHAKR1B1MEN1
SCHEMBL5031158 0.90 CES2 (0.48) CES2CES1FAAHMEN1KMT2A
SCHEMBL28557597 0.90 CES2 (0.48) CES2CES1FAAHMEN1KMT2A
SCHEMBL28374267 0.88 FAAH (0.62) FAAHMEN1KMT2ATP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 690 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368165-A Polyamide composition and method for stacking stone slabs 财团法人石材暨资源产业研究发展中心 2022-11-22 CN claimed
EP-3775048-A1 THERMOPLASTIC COMPOSITION Multibase SA (FR) 2021-02-17 EP claimed
EP-3775002-A1 THERMOPLASTIC COMPOSITION CONTAINING A MASTERBATCH OF A STICK-SLIP MODIFIER DDP SPECIALTY ELECTRONIC MATERIALS US 9, LLC. (US) 2021-02-17 EP claimed
US-20210024750-A1 THERMOPLASTIC COMPOSITION MULTIBASE SA (FR) 2021-01-28 US claimed
US-20210009768-A1 THERMOPLASTIC COMPOSITION DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) 2021-01-14 US claimed
EP-3349983-B1 FOOD PACKAGING JOHNSON MATTHEY PLC (GB) 2019-11-13 EP claimed
WO-2019195516-A1 THERMOPLASTIC COMPOSITION CONTAINING A MASTERBATCH OF A STICK-SLIP MODIFIER DOW SILICONES CORPORATION (US) 2019-10-10 WO claimed
WO-2019193192-A1 THERMOPLASTIC COMPOSITION MULTIBASE SA (FR) 2019-10-10 WO claimed
EP-3143070-B1 AMORPHOUS HIGH PERFORMANCE POLYAMIDE SHAKESPEARE CO LLC (US) 2019-08-14 EP claimed
US-20190136053-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE THEREFROM EMS-PATENT AG (CH) 2019-05-09 US claimed
EP-0290482-B1 TRANSDERMAL ABSORPTION DOSAGE UNIT FOR NARCOTIC ANALGESICS AND ANTAGONISTS AND PROCESS FOR ADMINISTRATION UNIV RUTGERS (US) 1995-03-08 EP claimed
EP-0429039-B1 Use of an opiate antagonist for the preparation of a pharmaceutical composition to be transdermally administered, and device for transdermal delivery ALKO LTD (FI) 1995-03-08 EP claimed
EP-0245126-B1 PERCUTANEOUS ABSORPTION PREPARATION AND PROCESS FOR PREPARING SAME Ogiso, Taro (JP) 1991-04-17 EP claimed
EP-0171062-B1 COEXTRUDED MONOFILAMENT FISHLINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-01 EP claimed
US-4873081-A CALCIUM SALT OF INDOMETHACIN OR TOLMETIN, A MEDIUM AND AN ABSORPTION PROMOTER; ANTIINFLAMMATORY MARAHO CO., LTD. (JP) 1989-10-10 US claimed
US-4743588-A Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents ALLERGAN PHARMACEUTICALS, INC. (US) 1988-05-10 US claimed
EP-0245126-A2 Percutaneous absorption preparation and process for preparing same Ogiso, Taro (JP) 1987-11-11 EP claimed
EP-0214859-A2 Microporous polymeric films and process for their manufacture E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-18 EP claimed
EP-0164998-A2 Compositions and methods of enhancing transdermal and transmembrane penetration of topical and systemic agents ALLERGAN, INC (US) 1985-12-18 EP claimed
US-4555566-A BLOCK POLYMER; HYDROXY TERMINATED, HYDROGENATED POLYOLEFIN DAICEL CHEMICAL INDUSTRIES, CO., LTD. (JP) 1985-11-26 US claimed