Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984615 | 1.00 | CES2 (0.45) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL1407233 | 1.00 | CES2 (0.45) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL5027330 | 1.00 | CES2 (0.45) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL27727796 | 1.00 | CES2 (0.45) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL123158 | 0.98 | CES2 (0.43) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL5038259 | 0.98 | CES2 (0.46) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL5031158 | 0.92 | CES2 (0.48) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL28557597 | 0.92 | CES2 (0.48) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL3738395 | 0.92 | CES1 (0.41) | CES2CES1FAAHMEN1KMT2A | |
| SCHEMBL28374267 | 0.90 | FAAH (0.62) | FAAHMEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059143-B1 | TOOTHBRUSH WITH INCLINED BRISTLES AND POINTED BRISTLES | GABA INTERNATIONAL AG (CH) | 2013-04-03 | — | — | EP | claimed |
| US-8239996-B2 | Toothbrush comprising inclined and tapered bristles | GABA INTERNATIONAL AG (CH) | 2012-08-14 | — | — | US | disclosed |
| US-20080271276-A1 | Toothbrush Comprising Inclined and Tapered Bristles | GABA INTERNATIONAL AG (CH) | 2008-11-06 | — | — | US | disclosed |